T-Cell Interferon Gamma Receptor Binding in Interferon Beta-1b–Treated Patients With Multiple Sclerosis

interferon-gamma gene polymorphism in iranian patients with multiple sclerosis

interferon- gamma (ifn- γ) is an important immune regulator and inflammatory cytokine which is implicated in the pathogenesis of multiple sclerosis (ms). a single nucleotide polymorphism, t to a, at position +874 in the first intron has previously been shown. this polymorphism is associated with ifn- γ production level. to study the effect of this polymorphism on susceptibility to multiple scle...

Inhibitory effect of the interferon-beta on the release of endothelial cell derived microparticles in patients with multiple sclerosis

Abstract Introduction: Increased levels of microparticles (MPs) have been reported in many autoimmune diseases such as multiple sclerosis (MS). In MS, endothelial cells release MPs from their membranes following the activation of lymphocytes and the production of inflammatory cytokines. The aim of this study was to investigate the inhibitory effect of interferon beta (INFβ) on the release of en...

P 52: Interferon beta-a1 vs. Teriflunomide for Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory disorder, in which neurons in central nervous system (CNS) become demyelinated .MS is named for its formation of plaques due to sclerosis of myelin. Variable degree of demyelination results in mild, mediate or severe symptomatic episodes of this disease. It is commonly characterized by recurrent relapses and often followed by severe neurological disabi...

Interferon-gamma gene polymorphism in Iranian patients with multiple sclerosis.

Interferon- gamma (IFN- gamma) is an important immune regulator and inflammatory cytokine which is implicated in the pathogenesis of multiple sclerosis (MS). A single nucleotide polymorphism, T to A, at position +874 in the first intron has previously been shown. This polymorphism is associated with IFN- gamma production level. To study the effect of this polymorphism on susceptibility to multi...

Interferon beta and suicide in multiple sclerosis.